研究方向(含承担课题)

重庆医科大学附属第一医院神经内科、国家卫健委功能性脑疾病诊治重点实验室副研究员。长期开展抑郁症研究，以第一作者在Molecular Psychiatry（IF=13.4； 2篇）、Briefings in Bioinformatics（IF=11.6）、Translational Psychiatry（IF=6.8）、Psychiatry and Clinical Neurosciences、Psychiatry Research等发表9篇SCI论文，以共同第一作者在Neurology、Translational Psychiatry等发表12篇SCI论文。并参与在Lancet、Nature Neuroscience、JAMA Psychiatry、Brain、Advanced Science等发表40余篇论文。主持国家自然科学基金2项、中国博士后科学基金1项等，累计获得科研经费500余万元，入选中国科协青年人才托举工程、重庆医科大学“揭榜挂帅”重大科技人才项目、重庆市中青年医学高端人才等。作为主要参与人荣获重庆市科技进步一等奖等学术荣誉。担任 Discover Mental Health （Springer出版社）等杂志编委。

著作论文

1. Pu J#, Liu Y#, Gui S#, Tian L, Yu Y, Song X, Zhong X, Chen X, Chen W, Zheng P, Zhang H, Gong X, Liu L, Wu J, Wang H, Xie P*. Metabolomic changes in animal models of depression: a systematic analysis. Molecular Psychiatry. 2021 Dec;26(12):7328-7336.

2. Pu J#, Liu Y#, Zhang H#, Tian L, Gui S, Yu Y, Chen X, Chen Y, Yang L, Ran Y, Zhong X, Xu S, Song X, Liu L, Zheng P, Wang H, Xie P*. An integrated meta-analysis of peripheral blood metabolites and biological function in major depressive disorder. Molecular Psychiatry. 2021 Aug;26(8):4265-4276.

3. Pu J#, Yu Y#, Liu Y#, Tian L#, Gui S, Zhong X, Fan C, Xu S, Song X, Liu L, Yang L, Zheng P, Chen J, Cheng K, Zhou C, Wang H, Xie P*. MENDA: a comprehensive curated resource of metabolic characterization in depression. Briefings in Bioinformatics. 2020;21(4):1455-1464.

4. Pu J#, Yu Y#, Liu Y, Wang D, Gui S, Zhong X, Chen W, Chen X, Chen Y, Chen X, Qiao R, Jiang Y, Zhang H, Fan L, Ren Y, Chen X, Wang H, Xie P. ProMENDA: an updated resource for proteomic and metabolomic characterization in depression. Translational Psychiatry 2024;14:229.

5. Pu J#, Liu Y#, Gui S, Tian L, Yu Y, Wang D, Zhong X, Chen W, Chen X, Chen Y, Chen X, Gong X, Liu L, Li W, Wang H, Xie P*. Effects of pharmacological treatment on metabolomic alterations in animal models of depression. Translational Psychiatry. 2022 Apr 29;12(1):175.

6. Pu J, Liu Y, Gui S, Tian L, Xu S, Song X, Zhong X, Chen Y, Chen X, Yu Y, Liu L, Zhang H, Wang H, Zhou C, Zhao L, Xie P*. Vascular endothelial growth factor in major depressive disorder, schizophrenia, and bipolar disorder: a network meta-analysis. Psychiatry Research. 2020 Jul 20;292:113319.

7. Pu J#, Liu X#, Liu Y#, Gui S, Zhong X, Tian L, Yang L, Xu S, Song X, Chen X, Chen Y, Wang H, Xu G*, Xie P*. Sex-specific plasma metabolome signatures in major depressive disorder. Psychiatry and Clinical Neurosciences 2019 Nov;73(11):713-714.

8. Pu J#, Zhou X#, Liu L#, Zhang Y, Yang L, Yuan S, Zhang H, Han Y, Zou D, Xie P*. Efficacy and acceptability of interpersonal psychotherapy for depression in adolescents: A meta-analysis of randomized controlled trials. Psychiatry Research. 2017 Jul;253:226-32.

9. Pu J#, Zhou X#, Zhu D#, Zhong X, Yang L, Wang H, Zhang Y, Fan S, Liu L, Xie P*. Gender differences in psychological morbidity, burnout, job stress and job satisfaction among Chinese neurologists: a national cross-sectional study. Psychology, health & Medicine. 2017 Jul;22(6):680-92.