研究方向(含承担课题)

主要从事抑郁症肠-脑轴分子机制研究，第一作者（含共同）在Nature Neuroscience（IF=25.0）、Molecular Psychiatry（IF=11.0）等杂志发表SCI论文4篇。作为课题组骨干成员，参与发表SCI论文6篇（其中IF>10，4篇），参与2项国家自然科学基金面上项目。

著作论文

1. Wu J#, Li Y#, Huang Y#, Liu L, Zhang H, Nagy C, Tan X, Cheng K, Liu Y, Pu J, Wang H, Perry SW, Turecki G, Wong ML, Licinio J, Zheng P*, Xie P*. Integrating spatial and single-nucleus transcriptomic data elucidates microglial-specific responses in female cynomolgus macaques with depressive-like behaviors. Nat Neurosci. 2023 Aug;26(8):1352-1364. doi: 10.1038/s41593-023-01379-4. IF=28.8

2. Huang Y#, Wu J#, Zhang H#, Li Y, Wen L, Tan X, Cheng K, Liu Y, Pu J, Liu L, Wang H, Li W, Perry SW, Wong ML, Licinio J, Zheng P*, Xie P*. The gut microbiome modulates the transformation of microglial subtypes. Mol Psychiatry. 2023 Apr;28(4):1611-1621. doi.org/10.1038/s41380-023-02017-y. IF=13.4

3. Tan X#, Huang Y#, Chai T, Zhao X, Li Y, Wu J, Zhang H, Duan J, Liang W, Yin B, Cheng K, Yu G, Zheng P, Xie P. Differential Gut Microbiota and Fecal Metabolites Related With the Clinical Subtypes of Myasthenia Gravis. Front Microbiol. 2020 Sep 8;11:564579. doi: 10.3389/fmicb.2020.564579. IF=4.2

4. Liang W#, Huang Y#, Tan X#, Wu J, Duan J, Zhang H, Yin B, Li Y, Zheng P, Wei H, Xie P. Alterations Of Glycerophospholipid And Fatty Acyl Metabolism In Multiple Brain Regions Of Schizophrenia Microbiota Recipient Mice. Neuropsychiatr Dis Treat. 2019 Nov 19;15:3219-3229. doi: 10.2147/NDT.S225982. IF=2.1