1. 自然抑郁猴动物模型的构建，笼养食蟹猴社会等级特点及影响因素；

2. 小胶质细胞外泌体在脑出血中的干预作用及机制探讨；

3. 构建复合纳米药物在脑出血中的治疗作用及机制探讨。

作为主要完成人之一，相关研究成果获得2021年度重庆市科技进步二等奖。

1. Xu F, Wu Q#, Xie L, Gong W, Zhang J, Zheng P, Zhou Q, Ji Y, Wang T, Li X, Fang L, Li Q, Yang D, Li J, Melgiri ND, Shively C, Xie P. Macaques exhibit a naturally-occurring depression similar to humans. Sci Rep. 2015 Mar 18;5:9220.

2. Zhou Q, Xu F, Wu Q#, Gong W, Xie L, Wang T, Fang L, Yang D, Melgiri ND, Xie P. The mutual influences between depressed Macaca fascicularis mothers and their infants. PLoS One. 2014 Mar 5;9(3):e89931.

3. Zhang W, Wu Q#, Hao S, Chen S. The hallmark and crosstalk of immune cells after intracerebral hemorrhage: Immunotherapy perspectives. Front Neurosci. 2023 Jan 12;16:1117999.

4. Zhang Y, Wang D, He Z, Wu Q, Zhou J. Hemicrania continua-like headache secondary to nasopharyngeal carcinoma: A case report. Cephalalgia. 2017 Sep;37(10):1005-1007.

5. Wen Y, Wu Q, Shi Q, Xie Y, Dan W, Chen Y, Ma L. UCH-L1 inhibition aggravates mossy fiber sprouting in the pentylenetetrazole kindling model. Biochem Biophys Res Commun. 2018 Sep 18;503(4):2312-2318.

6. Wang J, Wu Q, Du CP, Liu J, Zhang H, Wang JY, Xue W, Chen SL. Spontaneous cerebellar hemorrhage with severe brainstem dysfunction through minimally invasive puncture treatment by locating the simple bedside. Medicine (Baltimore). 2019 Sep;98(38):e17211.

7. 李炜, 吴青原, 连斌,等. 笼养食蟹猴攻击-屈服行为下的自然抑郁模型探究. 上海交通大学学报：医学版, 2018, 38(12):

8. Li X, Yang W, Shen Y, Liu F, Xiong X, Wu Q, Xiao Z, Yang X, Dang R, Manaenko A, Xie P, Li Q. Analysis of Age-Dependent Transcriptomic Changes in Response to Intracerebral Hemorrhage in Mice. Front Mol Neurosci. 2022 May 23;15:908683.

9. Dang R, Wang M, Li X, Wang H, Liu L, Wu Q, Zhao J, Ji P, Zhong L, Licinio J, Xie P. Edaravone ameliorates depressive and anxiety-like behaviors via Sirt1/Nrf2/HO-1/Gpx4 pathway. J Neuroinflammation. 2022 Feb 7;19(1):41.

10. 刘小芳,雷达,张文青,陈胜利,吴青原.以共济失调为主要临床表现的低血糖症(附2例报告及文献复习).中国临床神经科学,2023,31(01):100-104+110.